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胆囊息肉样病变103例临床及病理分析

Polypoid lesions of gallbladder:Clinical and histopathological analysis of 103 cases

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【作者】 张秋生常晓健崔惠敏彭侠彪

【Author】 Zhang Qiusheng *,Chang Xiaojian,Cui Huimin,et al. *Department of Gastroenterology,Zhongshan Municipal People’s Hospital,Zhongshan 528403,China

【机构】 广东省中山市人民医院消化内科广东省中山市人民医院普外科广东省中山市人民医院消化内科 (528403)(528403)(528403)

【摘要】 目的 探讨胆囊息肉样病变 (PLG)的临床表现、影像学、病理学特点。方法 对 10 3例PLG患者的临床、影像学、病理学及术后随访资料作统计分析。结果 胆固醇性息肉 5 4例 ,炎性息肉 34例 ,未见息肉 7例 ,胆囊肿瘤性息肉 (NPG) 8例 (腺瘤 6例、腺癌 2例 )。在直径≤ 5mm、6~ 10mm、11~ 15mm、>15mm组 ,NPG分别为 0(0 / 2 2 )、3例 (3/ 6 4 )、4例 (4 / 16 )、1例 (1/ 1) ,腺癌 2例直径均≥ 15mm ,NPG在直径 >10mm组多于≤ 10mm组。NPG中单发 6例 (6 / 8) ,非NPG中单发 2 7例 (2 7/ 95 )。术后中长期并发症发生率 32 8% (19/ 5 8)。结论 PLG应先做定期B超随访 ,出现下述表现之一者宜切除胆囊 :直径 >10mm、单发广基、随访中增大、伴有胆囊结石、症状明显或其它影像学检查提示NPG。

【Abstract】 Objective To investigate the relationship between clinical and ultrasonographic and histopathologic feature of polypoid lesions of gallbladder(PLG).Methods The data of 103 patients with PLG including clinical,ultrasonographic,histopathologic and follow-up results after cholecystectomy were analyzed.Results All PLG were found by ultrasonography;29 patients were diagnosed during physical examination and 74 by consulting doctors.Of them,54 cases were with cholesterol polyps,34 with chronic inflammatory polyps,7 without polyps,8 with neoplastic polyps of gallbladder(NPG,6 adenoma and 2 adenocarcinoma).In the groups of diameter≤5mm,6-10mm,11-15mm and >15mm,NPG were 0/22,3/64,4/16 and 1/1 respectively.Diameters of 2 adenocarcinomas were ≥15mm.The rate of NPG in the group of diameter >10mm was higher than that in the group of diameter ≤10mm.In 8 cases of NPG,the solitary polyps were 6;in 95 cases of non-NPG the solitary were 27.The accuracy of ultrasonography (96/103) was higher than that of CT common scan (7/19) compared with histopathology.The rate of post-cholecystectomy syndrome was 32.8%(19/58).Conclusions All patients with PLG should be followed up by ultrasonography at fixed periods.Cholecystectomy is suggested if one of the conditions,such as diameter >10mm,solitary sessile,growth during follow-up,associated with gallstone,obvious symptomatic or novel imaging techniques indicating NPG occurs.

  • 【文献出处】 中国实用内科杂志 ,Chinese Journal of Practical Internal Medicine , 编辑部邮箱 ,2004年04期
  • 【分类号】R735.8
  • 【下载频次】99
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