【摘要】 目的:探讨高血压患者颈动脉粥样硬化血管重构与脑梗塞发生的关系。方法:将201例高血压患者分为脑梗塞和非脑梗塞两组并进行颈动脉超声检查,测量颈动脉内膜-中层厚度(IMT)、颈动脉血管表面积(VA)、管腔截面积(LA)、斑块面积(PA)、面积狭窄率(RSA)、偏心指数(EI)、最窄处流速(Vs)和最窄处收缩期内径(Ds),计算动脉最大剪切率(SRs)。结果:VA、LA、RSA、PA、Vs、Ds、SRs两组比较均无显著性差异(P>0.05);而脑梗塞组的IMT、EI明显比非梗塞组的高(P<0.01)。结论:高血压患者脑梗塞的发生率与颈动脉粥样硬化血管偏心性重构密切相关。更多还原

【Abstract】 Objective: To explore the relationship between remodeling of carotid atherosclerosis and cerebral infarction in patients with hypertension disease. Methods: Two hundred and one patients with hypertension disease were divided into two groups(cerebral infarction group and non-cerebral infarction group), in which carotid atherosclerosis were studied by high resolution ultrasonography. The intima-medial thickness(IMT), vessel area(VA), lumen area(LA), plaque area(PA), rate of stenosis area(RSA), eccentric index(EI), systolic velocity (Vs), systolic diameter of lumen(Ds), and shear stress(SRs) were detected or calculated respectively. Results: The parameters of IMT, VA, LA, RSA, PA, Vs, Ds, SRs had no significant differences between the two groups. While the parameters of EI in the patients with cerebral infarction group were higher than those of non-cerebral infarction group and had significant differences(P<0.01). Conclusion: There were significant correlation between eccentric remodeling of carotid atherosclerosis and cerebral infarction.更多还原