【摘要】 目的　探讨小剂量多巴酚丁胺负荷超声 (LDDSE)结合心肌背向散射积分 (IBS)技术检测存活心肌的准确性。方法　对 18例经冠状动脉定量造影术 (QCA)确诊为冠心病患者行经皮冠状动脉介入治疗术 (PCI)。术前 1周内行LDDSE检查及采集IBS图像 ,术后 (3个月 )复查二维超声。分析在LDDSE过程中 ,以背向散射积分变异幅度 (CVIB)最大变化率 (K) >13定义为存活心肌 ,检测其识别存活心肌的准确性。并与单独用LDDSE的比较。结果　与LDDSE(5 μg,10 μg)相比 ,LDDSE结合IBS技术检测存活心肌敏感性、准确性明显提高 (91.84 %vs79.6 %、85 .7% ;91.0 7vs78.9%、85 .7% ,P <0 .0 5～ 0 .0 1)。结论　LDDSE结合IBS技术较LDDSE单独使用能提高检测存活心肌的敏感性和准确性。更多还原

【Abstract】 Objective To compare the accuracy of low dose dobut amine(Dob) stress echocardiography(LDDSE) and combination of integrated backscatter(IBS) for identifying survival myocardium in patients with coronary artery disease(CAD). Methods Percutaneous coronary intervention(PCI) was performed in 18 patients which were admitted for CAD by quantitative coronary artery(QCA). LDDSE was checked and IBS images were obtained before a week of PCI. Two-dimension echocardiography was examined after three months of PCI again. Defining the maximumal changing rate of CVIB(K) during LDDSE >13 as survival myocardium, then the accuracies in identifying survival myocardium were compared between LDDSE and LDDSE+IBS. Results The sensitivity, accuracy for identifying survival myocardium were significantly higher by LDDSE combined with IBS than those of LDDSE [5, 10 μg·kg -1·min -1] ( sensitivity: 91.84% vs 79.6%、 85.7%, P< 0.05- 0.01),accuracy: 91.07 vs 78.9%、 85.7% respectively P< 0.05- 0.01). Conclusion Identifying survival myocardium by LDDSE combined with IBS was more sensitive, accurate than LDDSE alone.更多还原