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三种替硝唑片剂的溶出度比较
Dissolution of three kinds of tinidazole tablets
【摘要】 目的:对三个厂家的替硝唑片的溶出度进行考察,比较其溶出参数,为临床选药提供理论依据。方法:用转篮法测定溶出度,紫外分光光度法测定溶出的度含量。结果:三个厂家的替硝唑片的溶出度均符合威布尔模型。结论:三者的溶出度参数TD、T30、T50、T80及m均存在显著差异。
【Abstract】 Objective: To inspect the dissolutions of three factories of Tinidazole tablets. Methods: The dissolution was performed in a ratating shaker. The content was determined by UV method. Results: The dissolutions of the three factories of Tinjdazole accord with the Model of Weibubll. Conclusion: The three factories of the main parameters,such as T ,TD,T , T and m,have very significant difference.
【关键词】 替硝唑片;
溶出度;
转篮法;
紫外分光光度法;
【Key words】 Tinidazole tablets; Dissolution; Rotating shaker; UV method;
【Key words】 Tinidazole tablets; Dissolution; Rotating shaker; UV method;
- 【文献出处】 抗感染药学 ,Anti-infection Phurmacy , 编辑部邮箱 ,2004年01期
- 【分类号】R927.11
- 【被引频次】2
- 【下载频次】72