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氟伐他汀对老年2型糖尿病血脂影响的临床观察

Clinical investigation of Fluvastatin on blood lipids in elderly type Ⅱ diabetes mellitus patients

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【作者】 刘波徐冬岩门兰张磊段秀康郑春艳卢丹姚文华

【Author】 LIU-Bo,XU Dong-yan,MEN Lan,et al (China Japan Union Hospital of Jilin University, Changchun 130031,China)

【机构】 吉林大学中日联谊医院内分泌科江苏省常州市武进医院通榆县中医院吉林大学中日联谊医院内分泌科 吉林长春130023吉林长春130023江苏常州213000吉林通榆137200吉林长春130023

【摘要】 目的观察氟伐他汀在老年2型糖尿病合并高脂血症患者中对血脂水平的影响。方法选择72例老年2型糖尿病合并高脂血症患者,随机分成2组,在控制饮食的基础上分别给予氟伐他汀40mg/d和单纯降糖治疗8周,分别测定治疗前后的血脂水平。结果应用降血脂药物后,患者的TG、CHO、LDL降低,HDL升高,血脂紊乱得到明显纠正。结论氟伐他汀对老年2型糖尿病合并高脂血症患者有明显的调脂作用,它可使TG、CHO、LDL降低,使HDL升高。

【Abstract】 objective to investigation the clinical effect of Fluvastatin on blood lipids in elderly type 2 diabetes mellitus patients accompanied with hyperlipemia. Method 72cases of elderly type 2 diabetes mellitus patients accompanied with hyperlipemia were randomly divided into two groups, on the base of food control, one was treated with Fluvastatin 40 mg/d for eight weeks, the other was treated with only antihyperglycemic, then blood lipids were estimated before and after treatment. Results After treatment with Fluvastatin, TG, CHO, LDL were reduced and HDL was increased. Dyslipidemia was obviously corrected. Conclusion For elderly type 2 diabetes mellitus patients accompanied with hyperlipemia, Fluvastatin is effective in adjusting blood lipids. Fluvastatin can reduce TG, CHO, LDL,and increase HDL.

【关键词】 氟伐他汀2型糖尿病高脂血症
【Key words】 FluvastatinType 2 diabetes mellitusHyperlipemia
  • 【文献出处】 吉林医学 ,Jilin Medical Journal , 编辑部邮箱 ,2004年06期
  • 【分类号】R587.1
  • 【被引频次】4
  • 【下载频次】24
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