【摘要】 通过研究微生物降解卤素化合物发现了不同种类的去卤化酶,这些酶可以在好氧或厌氧条件下通过不同的作用机理脱去卤原子催化降解卤素化合物。到目前,通过生物法得到将近4000多种卤素化合物,早期仅分离并获得了催化卤化反应的卤过氧化物酶,近来,在研究细菌卤化代谢物的生物合成时发现了以FADH2为辅基的卤化酶。这种新型的卤化酶在卤化代谢物的生物合成中起催化作用。更多还原

【Abstract】 Study on the degradation of halocompounds by microorganisms have led to the detection of various dehalogenating enzymes catalyzing the removal of halogen atoms under aerobic and anaerobic conditions involving different mechanisms. Presently, nearly 4000 halocompounds were produced biologically. Several years ago, only haloperoxidases which catalyze halogenation reactions were detection. Recent investigations into the biosynthesis of halogenated metabolites by bacteria have shown that a novel type of halogenating enzymes, FADH₂-dependent halogenases, are involved in biosyntheses of halogenated metabolites.更多还原