【摘要】 目的　动态观察山东省克山病病情 ,为科学防治提供依据。方法　按照全国克山病监测方案要求 ,在克山病重病区设立监测点 ,对 3～ 14岁易患人群及 14岁以上可疑患者进行连续 5年病情监测 ,同时调查内外环境硒、经济收入及人均占有粮食。结果　自 1990年至 2 0 0 2年已连续 13年进行了病情监测 ,4个监测点区县无急型、亚急型克山病发病 ,慢型克山病发病 7例 ;重点检测人群克山病检出率在 1. 81%～ 4. 2 3 %之间 ,其中 81. 3 %～ 94. 6%为潜在型克山病人 ;异常心电图和X线胸片心脏扩大检出率分别是 2 . 10 %～ 5 . 71%和 15 . 5 0 %～ 2 3 . 60 %,与非病区无明显差异 (P >0 . 0 5 ) ;发硒含量有增加趋势。结论　山东省克山病病情处于基本控制后的持续稳定状态更多还原

【Abstract】 Objective\ In order to observe change of condition of Keshan disease (KSD) in Shandong and supply evidence for scientific control and study. Method\ According to scheme of condition surveillance of KSD in endemic areas of Shandong Province, the surveillance field of KSD were set up in endemic area. Result\ The susceptible children (3～14 years) and suspicious patients (over 14 years) were observed for 5 years in surveillance field. At the same time selenium in and out environment was determined and life condition of inhabitant was surveyed. The condition surveillance was kept on from 1990 to 2002. Acute and subacute cases were not present but 7 patients with chronic disease occurred in 4 counties. The incidence of KSD in key surveillance subjects was from 1.81% to 4.23%. There was latent KSD from 81.3% to 94.6% among them. The incidence of abnormal electrocardiogram (ECG) was from 2.1% to 5.71%. The incidence of enlarged heart was from 15.5% to 23.6%. There is not obvious difference in abnormal ECG and enlarged heart between people from endemic area and nonendemic areas(P>0.05). Selenium content of hair was increased. Conclusion\ The condition of Keshan disease was in steady stituation in Shandong.更多还原