【摘要】 在氩气的保护下,用LiAlH4还原体系在35℃,用NaBH4/BF3,NaBH4/I2还原体系在0℃,分别对酰亚胺(R,R)1-苄基-2,5-二氧-3,4-二羟基吡咯啉进行还原,得到相应的叔胺(S,S)1-苄基-3,4-二羟基吡咯啉,测量了产物的熔点,并用红外图谱表征了叔胺的结构,产率分别为66%,58%和63%.最后对硼烷和LiAlH4还原酰亚胺可能的机理进行了讨论.更多还原

【Abstract】 Imide （R,R）1-benzyl-2,5-dioxo-3,4-dihydroxy-pyrrolidine was reduced by NaBH₄/I₂,NaBH₄/BF₃ under argon atmosphere at 0 ℃, and by LiAlH₄ under argon atmosphere at 35 ℃ separately. Thus the corresponding tertiary-amide （S,S）1-benzyl-3,4-dihydroxy-pyrrolidine was produced, and the yield was 63%,58% and 66%. The melting point of each product was measured and the structure characterized by infrared spectroscopy. The reduction mechanism of diborane and LiAlH₄ was finally discussed.更多还原