【摘要】 ①目的　评价海洋低温溶菌酶对阴道炎常见致病菌的体外抗菌活性。②方法　采用琼脂平皿二倍稀释法测定海洋低温溶菌酶对阴道炎常见致病菌白色念珠菌、生孢梭菌以及金黄色葡萄球菌、大肠埃希菌的最低抑菌浓度 (MIC)和最低杀菌浓度 (MBC)。③结果　海洋低温溶菌酶对白色念珠菌、生孢梭菌、金黄色葡萄球菌、大肠埃希菌均有较好的抗菌活性 ,其MIC分别为 39.0 7、9.75、1 0 .94、1 0 .94 μmol/L ,MBC分别为 39.0 7、1 9.5 7、1 0 .94、2 1 .88μmol/L。 ④结论　海洋低温溶菌酶对一些阴道炎常见致病菌有较好的抗菌活性更多还原

【Abstract】 Objective To investigate the in vitro antibacterial activity of marine low-temperature lysozyme against several pathogens of vaginitis. Methods The minimal inhibitory concentrations (MIC) and minimal bactericidal concentrations (MBC) of the lysozyme against Candida albicans, Clostridium sporgenes, Staphylococcus aureu and Escherichia coli were tested by standard agar dilution method. Results The MIC of the lysozyme against Candida albicans, Clostridium sporogenes, Staphylococcus aureu and Escherichia coli were 39.07,9.75,10.94,10.94 μmol/L, respectively, while the MBC of it were 39.07,19.57,10.94, 21.88 μmol/L . Conclusion Marine low-temperature lysozyme has fairly good antibacterial activity for common pathogens causing vaginitis.更多还原