【摘要】 随着分子影像学的发展,可以利用放射性核素报告基因显像技术探测基因治疗中治疗基因表达情况。目前主要有两种报告基因系统———编码细胞内的酶和细胞表面受体的报告基因。更多还原

【Abstract】 Molecular nuclear imaging techniques are currently being developed to map the topography and level of gene expression following gene therapy. To date, two radionuclide-based imaging strategies have been investigated--using reporter genes encoding either intracellular enzymes or cell-surface receptors. In this article, we discuss these two reporter gene imaing systems that have been developed to detect gene expression noninvasively.更多还原