【摘要】 研究了沙质荒漠区双峰驼以消瘦、异嗜、运动障碍和容易骨折为特征的疾病。通过检测病驼食物链系统及全血、被毛和组织器官中 10种矿物元素 (Ca、P、Cu、Fe、Zn、Co、Mn、F、Se、Mo)的含量 ,分析血液临床化学指标的变化并进行组织病理形态学研究。结果表明 ,病区土壤、牧草Cu、P含量显著低于正常区 (P <0 .0 1) ,牧草Ca∶P为5 0∶1,病驼全血、被毛和肋骨P含量显著低于健康驼 (P <0 .0 1) ,病驼血清PTH、T3 、T4、Crt含量和ALP、LDH活性极显著升高 (P <0 .0 1) ,病理组织学证明全身性骨损伤为典型的骨质疏松。认为该病主要是由食物链中P缺乏所致的骨质疏松症。更多还原

【Abstract】 A disease characterized by emaciation, pica, lameness and liability to fracture in bactrian camels from gravel desert pasture was described. Analyses of mineral elements in soil, water and forage from the affected and normal areas as well as in blood, hair and parts of tissues from normal and diseased camels, together with a pathological study were carried out to define the nature and major causes of the disease. The related blood indices were also measured. The result indicated that the concentrations of copper and phosphorus in the soil and forage from the affected area were significantly lower than those of the normal area (P<0.01). m (Ca)∶m (P) ratio in forage was 50∶1. The concentrations of phosphorus in the blood, hair and rib reduced significantly in affected camels. The concentrations of PTH, T 3, T 4, creatinine (Crt) and the activity of alkaline phosphatase (ALP) and lactate dehydrogenase (LDH) in serum rose markedly (P<0.01). Bone injury was shown to be a kind of osteoporosis by histopathological study. It is concluded that the disease was caused mainly by phosphorus deficiency in the food chain.更多还原