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门静脉高压症大鼠肠道推进功能的实验性研究

THE OBSERVATION OF INTESTINAL TRANSIT IN PORTALHYPERTENSIVE RAT

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【作者】 何美文戴植本朱立元

【Author】 He Meiwen, Dai Zhiben, Zhu Liyuan. The ShenZhen Hospital of Beijing University, by Guang Dong 518036

【机构】 北京大学深圳医院普外科华中科技大学同济医学院附属同济医院外科北京大学深圳医院普外科 广东省深圳市518036广东省深圳市518036

【摘要】 目的 检测门静脉高压症大鼠肠道推进功能。方法 门静脉高压症模型制成后的第二和第十天 ,按 1ml/ 1 0 0 g体重分别给大鼠管饲肠道染色剂 ,2 5min后 ,测量小肠全长及被染色的长度 ,把被染色小肠长度占小肠全长的百分比作为小鼠推进功能指标。结果 实验组两个时间的小肠推进功能明显低于对照组 ,P <0 .0 1差异有高度显著性。结论 小肠推进功能减弱、食物淤滞、细菌过度生长 ,可能是引起门静脉高压症大鼠肠道细菌移位的一个重要原因。

【Abstract】 Objective The Intestinal Transit Probe of Portal hypertensive rat. Methods Intestinal coloring agents in dose of 1ml/100g were given throught cube to rats in the second and ten days after the portal hypertersive model was made respectively,25 mins later,whole small Bowel and colored section were measured.the rat of colored to whole length was calculated. which is regarded as a indicator of intestinal transit. Resultes The Result shows that the intestinal transit in test group is obviously weaker than that in control group in two phases,P<0.01, there is significant difference between two groups. Conclusion The weaken of intestinal transit. the stasis of food and bacterial overgrowth may be the improtant causes of bacterial transiocation.

【关键词】 门静脉高压症大鼠肠道推进功能
【Key words】 portalhypertensionratIntestinaltransit
  • 【文献出处】 中国煤炭工业医学杂志 ,Chinese Journal of Coal Industry Medicine , 编辑部邮箱 ,2003年01期
  • 【分类号】R657.34
  • 【下载频次】28
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