【摘要】 目的　探讨尿路感染病原菌的分布及耐药性特征 ,为临床合理选用抗生素、控制医院感染提供依据。方法　收集我院尿路感染患者标本中分离的 15 1株病原菌进行鉴定 ,同时对G-杆菌进行ESBLs的检测 ,肠球菌属进行氨基糖苷类高水平耐药 (HLAR)的筛选。结果　尿路感染病原菌分布占前几位的细菌为大肠埃希菌5 3 6 4 %、肠球菌属 9 2 7%、凝固酶阴性葡萄球菌 7 95 %、假单胞菌 5 96 % ;产ESBLs大肠埃希菌的检出率为13 5 8% ,产ESBLs肺炎克雷伯菌的检出率为 16 6 7% ,HLAR肠球菌属检出率为 5 7 14 %。结论　重视尿路感染病原菌耐药性检测 ,对控制医院感染、合理使用抗生素十分重要更多还原

【Abstract】 OBJECTIVE To determine distribution of pathogens and resistance characteristic and to provide basis for clinicians to select antibiotics correctly and control nosocomial infection. METHODS A total of 151 strains of pathogens were identified. ESBLs-producing G - bacteria were detected and high-level aminoglycoside resistance in Enterococcus(HLAR) were screened. RESULTS Among 151 strains, 53.64% Escherichia coli, 9.27% Enterococcus, 7.95% coagulase negative Staphylococcus and 5.96% Pseudomonas were detected. 13.58% E.coli and 16.67% Klebsiella pneumoniae produced ESBLs. HLAR-producing Enterococcus was 57.14%. CONCLUSIONS Much attention should be paid to resistance detection in urinary infection. It is important to control nosocomial infection and select antibiotics correctly.更多还原