【摘要】 目的　制定冠心病危险因素的定量评价标准 ,为预测个体冠心病的患病危险奠定基础。方法　通过文献检索收集冠心病危险因素的病例对照和队列研究资料及四川省的行为危险因素监测资料 ,运用meta分析软件对各危险因素与冠心病的比值比 (OR)、相对危险度 (RR)值进行合并 ,运用统计模型将不同暴露水平的危险因素转换成危险分数。结果　以 5岁为 1个年龄组 ,建立了 15～ 6 9岁不同性别的冠心病主要危险因素 :吸烟、被动吸烟、高血压、高血脂、体重指数、体育锻炼、饮酒、高脂饮食、糖尿病、冠心病家族史和高血压家族史的定量评价标准 (危险分数转换表 ) ,无这些危险因素 (体育锻炼除外 )者其危险分数均≤ 1 0 0 (进行体育锻炼者危险分数 <1 0 0 ) ,而伴有这些危险因素者其危险分数均 >1 0 0 ,且危险分数随危险程度的增加而增高。结论　冠心病危险分数转换表是计算冠心病存在死亡危险的基础 ,后者可预测个体未来 10年发生冠心病死亡的危险性。该方法是健康教育的有力依据 ,也是当前深入开展社区卫生服务的重要方法。更多还原

【Abstract】 Objective To set a quantitative criteria for determining risk for coronary heart disease (CHD) so that potential risk of an individual dying from CHD can be identified and to lay a foundation for predicting individual risk of CHD. Methods Data of case-control and cohort studies published during 1978 to 2002, as well as data of surveillance of behavior exposure in Sichuan province, were collected by retrieval of literatures.Pooled odds ratios ( OR ) and relative risks ( RR ) of all risk factors for CHD were estimated using various statistical models with software for meta-analysis, and attributable risk fractions of varied levels of risk factors could be converted. Results A risk score conversion table (quantitative criteria for assessment) of main risk factors for CHD were developed for men and women aged 15-69 at an interval of five years, including smoking, passive smoking, hypertension, high blood cholesterol level, body mass index, lack of physical activity, alcohol drinking, past history of diabetes, and family history of CHD and hypertension.Individuals with all these risk factors had a risk score beyond 1.00, and risk score for those without them was equal to or below 1.00, which would increase with rise in one’s risk level. Conclusions Estimation of risk of dying from CHD was based on risk score conversion table of risk factors for CHD, which could be used to predict individual potential risk of dying from CHD in the following 10 years.It lays a foundation for health education to persuade people to change their unhealthy lifestyles and behaviors, and could be used in community health services.更多还原