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中国幽门螺杆菌感染流行病学Meta分析

Meta-analysis on the epidemiology of Helicobacter pylori infection in China

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【作者】 王凯娟王润田

【Author】 WANG Kai-juan, WANG Run-tian. Department of Epidemiology and Statistics, School of Public Health, Peking University, Beijing 100083, China

【机构】 北京大学医学部公共卫生学院流行病与卫生统计学系教研室北京大学医学部公共卫生学院流行病与卫生统计学系教研室 100083100083

【摘要】 目的 综合分析中国幽门螺杆菌 (Hp)流行状况。方法 采用Meta分析对中国 1990~2 0 0 2年发表的有关Hp流行病学文献进行汇总、归纳和统计学分析。 结果 共检索 3 5 6 4篇文献 ,Hp感染在我国分布广泛 ,平均感染率为 5 8.0 7%,10~ 2 0岁组已达 5 0 %以上 ,Hp感染呈现明显的家庭聚集性。Hp是胃肠疾病发生的危险因素。 结论 中国为Hp高感染率地区 ,家庭内传播可能是Hp感染的主要途径。Hp感染与胃部疾病有关联性 ,开展Hp感染和相关疾病的防治意义重大。

【Abstract】 Objective To understand the epidemiologic features and etiology of Helicobacter pylori (H.pylori ) infection in China so as to provide evidence for the development of preventive measures on H.pylori infection and related diseases. Methods Meta-analysis was used to evaluate the data extracted from 1990-2002 published papers on the epidemiology of H.pylori infection in China. Results The average infection rate of H.pylori infection in China was 58.07%, with 50% in 10 to 20 year-olds. Significant intrafamilial clustering was observed. H.pylori infection was a risk factor to develop gastrointestinal disease. Conclusions H.pylori infections in Chinese were common and extensively distributed,which might due to close contact between family members. [

【关键词】 幽门螺杆菌流行病学Meta分析
【Key words】 Helicobacter pyloriEpidemiologyMeta analysis
  • 【文献出处】 中华流行病学杂志 ,Chinese Journal of Epidemiology , 编辑部邮箱 ,2003年06期
  • 【分类号】R181.3
  • 【被引频次】423
  • 【下载频次】6079
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