【摘要】 目的　探讨颌面部骨肉瘤的临床病理特征。方法　对 6 1例颌面部骨肉瘤进行临床资料分析、组织学观察及随访 ,并进行统计学分析。结果　患者男女之比 1 2 6∶1,平均年龄 39 8岁 ,上颌骨占 32 8% ,下颌骨占 5 7 4 %。成骨细胞型占 5 5 7% ,成软骨细胞型占 16 4 % ,成纤维细胞型占2 1 3%。各型骨肉瘤的共同组织学特点为恶性肿瘤细胞直接成骨。肿瘤复发率 39 1% ,肺转移率8 7%。结论　颌面部骨肉瘤最常见于下颌骨 ,性别无明显差异 ,好发年龄段较长骨骨肉瘤提高 10余岁。组织学分型上以成骨细胞型为主。肿瘤复发率较高 ,远处转移率较低 ,生物学行为较长骨骨肉瘤为好。更多还原

【Abstract】 Objective To study the clinicopathology of osteosarcoma in oral and maxillofacial region. Methods Clinical, histopathological features of 61 cases of osteosarcoma in oral and maxillofacial region were studied. Results The ratio of male to female was 1.26∶1, with the mean age 39.8. 32.8% cases were occurred in maxilla and 57.4% cases in mandible. Histologically 55.7% were osteoblastic, 16.4% were chondroblastic and 21.3% were fibroblastic. All tumors presented common histological feature that the neoplastic cells produced neoplastic bone.The recurrence rate of the tumor was 39.1% and the metastasis rate to lung was 8.7%. Conclusions Oral and maxillofacial osteosarcoma was most frequently occurred in mandible. There was no significant difference in patient’s gender. Patients were about 10 years older than those suffered the tumor in long bone . Osteoblastic type was the most commonly occurred histological type. The recurrence rate of the tumor was relatively high and the metastasis rate to lung was low. It seems that the tumor had good prognosis than osteosarcoma of long bone.更多还原