【摘要】 为了解苦豆子碱（Aloperine）消毒液杀菌效果与毒性,进行了载体定量杀菌试验与动物毒性试验。结果,1:1倍稀释的苦豆子碱消毒液对大肠杆菌作用5 min,对白色念珠菌作用10 min,对金黄色葡萄球菌作用15 min,对淋病奈瑟菌作用20 min,平均杀灭率均可达99.90％以上。有机物的存在对其杀菌作用有一定影响,对金属无腐蚀作用。经54℃温箱放置14d,杀菌效果不变。其原液对小鼠急性口服毒性LD₅₀>5000 mg/kg;对家兔皮肤粘膜及阴道粘膜无刺激性。结果表明,苦豆子碱消毒液对细菌繁殖体具有一定杀灭效果,使用安全性比较好。更多还原

【Abstract】 In order to know the germicidal efficacy and toxicity of aloperine disinfectant solution, carrier quantitative germicidal test and animal toxicity test were carried out. The results showed that the average kil-ling rates of Escherichia coli exposed to 1 : 1 diluted aloperine disinfectant solution for 5 min, Candida albicans exposed for 10 min, Staphylococcus aureus exposed for 15 min and Neisseria gonorrhoeae exposed for 20 min could attain over 99.90%. Presence of orgainc substance had certain influence on its germicidal ef-ficacy. It had no corrosive effect on metals. Its germicidal efficacy did not change after storing in 54癈 incu-bator for 14 days. The oral LD50 of its stock solution for mice was > 5 000 mg/ kg. It was not irritative to skin, mucous membrane and vaginal mucous membrane of rabbit. The results indicate that aloperine disin-fectant solution has certain killing effect on vegetative form of bacteria and good safety for use.更多还原