【摘要】 目的 :对光皮木瓜 (Chaenomelessinensis (Thouin)Koehne)枝条部分的甲醇提取物的乙酸乙酯萃取部分进行化学成分研究。方法 :利用多种色谱方法进行成分分离 ,根据物理化学性质和波谱学手段对化合物进行结构鉴定。结果 :初步分离得到 7个五环三萜类化合物 ,分别鉴定为古柯二醇 (erythodiol 1 ) ,马斯里酸 (masilinicacid 2 ) ,白桦脂酸 (betulinicacid 3) ,2α 羟基白桦脂酸 (2α hydroxybetulinicacid 4 ) ,白桦脂醇 (betulin 5 ) ,3 (E) p 香豆酰基白桦脂醇 (3 (E) p coumaroylbetulin 6 ) 3 (Z) p 香豆酰基白桦脂醇 (3 (Z) p coumaroylbetulin 7) ,其中化合物 1 ,2 ,4 ,5 ,6 ,7为木瓜属中首次分离得到的已知化合物更多还原

【Abstract】 AIM:To isolate and to identify the anticancer constituents of EtOAc soluble fraction of the MeOH extract of Chaenomeles sinensis (Thouin) Koehne. METHOD:Compounds were isolated by the silica gel columns, preparative TLC and HPLC, and their structures were identified by the physical and chemical properties especially by the spectral analysis. RESULT:Seven compounds were obtained and they were identified as erythodiol (1), masilinic acid(2), betulinic acid(3), 2α hydroxy betulinic acid(4), betulin (5), 3 (E) p coumaroylbetulin(6), 3 (Z) p coumaroylbetulin (7). CONCLUSION: Compounds 1, 2, 4, 5, 6 and 7 are obtained from the Chaenomeles genus for the first time.更多还原