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标准化皮试与特异性IgE测定在检测特异性过敏原中的比较
Comparison between Standardized Skin Prick Test and Specific IgE Determination in the Detection of Specific Allergen
【摘要】 目的:比较标准化皮试和特异性IgE测定对过敏性哮喘患者检测特异性过敏原的作用和意义。方法:对52例哮喘患者分别作以下检测:采用国际标准化的Allergopharma过敏原皮试液(共12种)作点刺试验;采用UniCAP过敏原检测系统作混合吸入物过敏筛选试验(Phadiatop试验)。结果:52例哮喘患者中标准化皮试阳性者45例(占86.5%),其中粉尘螨阳性者42例(占93.3%)。52例哮喘患者中Phadiatop试验阳性者47例(90.4%),其中44例(93.6%)标准化皮试同时为阳性;5例Phadiatop阴性者中4例皮试呈阴性。标准化皮试与Phadiatop试验的总符合率为92.3%(48/52)。结论:采用国际标准化的皮试液作点刺试验同时辅以Phadiatop试验阳性或阴性对照判断结果,可作为吸入性过敏原特异性诊断较为可靠的标准化手段。
【Abstract】 YObjective:To compare the standardized skin prick test with specific IgE determinaton in the detection of specific allergen in patients with allergic asthma.Methods:Fifty-two cases of allergic asthma were involved in this study as following methods:skin prick test with12international standardized Allergopharma reagents of allergen and UniCAP Phadiatop test(anaphylactic screening test)with mixture of inhalant allergens.Results:Of the52cases,45(86.5%)were positive in skin test,which mainly were dust mite(93.3%,45/47).Forty-seven cases(90.4%)were positive in Phadiatop test.Of the47cases,44(93.6%)were meanwhile positive in skin test,while in5negative cases of Phadiatop test,4were also negative in skin test.The total coincidence rate of these two tests was92.3%(48/52).Conclusions:It is credible to co-use the skin test with international standardized reagents of allergen and the Phadiatop test in the detection of specific aeroallergen
- 【文献出处】 诊断学理论与实践 ,Journal of Diagnostics , 编辑部邮箱 ,2003年01期
- 【分类号】R446.6
- 【被引频次】10
- 【下载频次】80