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标准化皮试与特异性IgE测定在检测特异性过敏原中的比较

Comparison between Standardized Skin Prick Test and Specific IgE Determination in the Detection of Specific Allergen

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【作者】 姚苏杭许以平朱丽君邹寒冰王菁兰吴祖群

【Author】 AO Suhang,XU Yiping,ZHU Lijun,et al.Department of Respiratory Medicine,Renji Hospital,Shanghai Second Medical University,Shanghai(200001)

【机构】 上海第二医科大学附属仁济医院呼吸科上海第二医科大学附属仁济医院呼吸科 200001200001200001

【摘要】 目的:比较标准化皮试和特异性IgE测定对过敏性哮喘患者检测特异性过敏原的作用和意义。方法:对52例哮喘患者分别作以下检测:采用国际标准化的Allergopharma过敏原皮试液(共12种)作点刺试验;采用UniCAP过敏原检测系统作混合吸入物过敏筛选试验(Phadiatop试验)。结果:52例哮喘患者中标准化皮试阳性者45例(占86.5%),其中粉尘螨阳性者42例(占93.3%)。52例哮喘患者中Phadiatop试验阳性者47例(90.4%),其中44例(93.6%)标准化皮试同时为阳性;5例Phadiatop阴性者中4例皮试呈阴性。标准化皮试与Phadiatop试验的总符合率为92.3%(48/52)。结论:采用国际标准化的皮试液作点刺试验同时辅以Phadiatop试验阳性或阴性对照判断结果,可作为吸入性过敏原特异性诊断较为可靠的标准化手段。

【Abstract】 YObjective:To compare the standardized skin prick test with specific IgE determinaton in the detection of specific allergen in patients with allergic asthma.Methods:Fifty-two cases of allergic asthma were involved in this study as following methods:skin prick test with12international standardized Allergopharma reagents of allergen and UniCAP Phadiatop test(anaphylactic screening test)with mixture of inhalant allergens.Results:Of the52cases,45(86.5%)were positive in skin test,which mainly were dust mite(93.3%,45/47).Forty-seven cases(90.4%)were positive in Phadiatop test.Of the47cases,44(93.6%)were meanwhile positive in skin test,while in5negative cases of Phadiatop test,4were also negative in skin test.The total coincidence rate of these two tests was92.3%(48/52).Conclusions:It is credible to co-use the skin test with international standardized reagents of allergen and the Phadiatop test in the detection of specific aeroallergen

  • 【文献出处】 诊断学理论与实践 ,Journal of Diagnostics , 编辑部邮箱 ,2003年01期
  • 【分类号】R446.6
  • 【被引频次】10
  • 【下载频次】80
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