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HPLC法分析炮制对虎杖中大黄素影响

Influence of processing Rhizoma Polygoni Cuspidati on its content of emodin

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【作者】 江海燕朱华陈勇蒋利林

【Author】 JIANG Hai-yan, ZHU Hua, CHEN Yong, JIANG Li-lin (Faculty of Pharmacy, Guangxi Traditional Chinese Medical University, Nanning, 530001, China)

【机构】 广西中医学院药学院广西中医学院药学院 广西南宁530001广西南宁530001广西南宁530001

【摘要】 目的 :探讨炮制对虎杖中大黄素含量的影响。方法 :采用高效液相色谱法进行测定。结果 :虎杖及各炮制品中大黄素的含量按如下顺序减少 :酒炙品 >醋炙品 >90℃ 3 0min烘品 >60℃ 60min烘品 >90℃ 60min烘品 >盐炙品 >生品 ,各炮制品中大黄素的含量与生品相比差异显著。结论 :炮制辅料、温度及时间能使虎杖中大黄素的含量产生变化

【Abstract】 Objective: To investigate the effects of processing on content of emodin in Rhizoma Polygoni Cuspidati. Method: The contents of emodin in Rhizoma Polygoni Cuspidati and in the different processed products of Rhizoma Polygoni Cuspidati were determined by HPLC. Results: The contents of emodin in Rhizoma Polygoni Cuspidati changed as follows: sample baked with rice wine >sample baked with vinegar >sample unprocessed dried at 90℃, 30min >sample unprocessed dried at 60℃, 60min >sample unprocessed dried at 90℃, 60min >sample baked with salt and then dried >unprocessed sample. The statistics analysis showed that the emodin contents in raw Rhizoma Polygoni Cuspidati were significantly different from those in the different processed products of Rhizoma Polygoni Cudpidati. Conclusion: The processing temperature and time, wine, vinegar and salt could make the contents of emodin in Rhizoma Polygoni Cuspidati change in different degree.

【关键词】 虎杖炮制大黄素HPLC
【Key words】 Rhizoma Polygoni CuspidatiprocessingemodinHPLC
【基金】 广西自然科学基金资助项目 (桂科自 0 135 0 2 8)
  • 【文献出处】 中成药 ,Chinese Traditional Patent Medicine , 编辑部邮箱 ,2003年06期
  • 【分类号】R283
  • 【被引频次】14
  • 【下载频次】227
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