【摘要】 [目的]从宏观行为学角度证实情志疾病基本病机—气机失调的客观存在及复方中药的干预作用。[方法]采用多项心理应激结合小剂量链脲佐菌素腹腔注射的复合方式 ,模拟心理应激诱发实验性2型糖尿病的大鼠模型 ,借鉴经典的旷场实验方法评定心理应激对2型糖尿病大鼠行为的影响 ,同时观察了具有理气、降逆散结作用的复方中药心身5号的调节作用。[结果]心理应激可导致实验性2型糖尿病大鼠的行为异常 ,心身5号可调节异常的行为改变。[结论]心理应激诱发实验性2型糖尿病大鼠行为异常是气机失调的外在宏观表现 ,反映情志疾病的共同病机气机失调的客观存在 ,及具有理气降逆散结作用的复方中药心身5号具有明显的调节效应更多还原

【Abstract】 Objective To verify the presence of qi disorder of psychosomatic diseases objectively from macroscopic behavior science and to study the interveution of Chinese medicine. The rat model with diabetes 2 was induced by various kinds of psychosomatic stress and small dosage STZ. The behavior influence of rats with diabetics 2 was assessed by classic Open Field Test. The regrlation effect of XinshenⅤ, a patent medicine with the function of regulating qi, lowering the reverse, dispeling the hard mass, was observed. Psychological stress could cause abnormal behavior in rats with diabetics 2.[Conclusion] The abnormal behavior of rats with experimental diabetes 2 induced by psychological stress is the macroscopic appearance of qi disorders and XinshengⅤcan regulate it markedly.更多还原