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硝苯地平缓释片释放过程的灰色数学模型

The Grey Model of Nifedipine Sustained —release Tablets in Release

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【作者】 杨保华王荔陈勇敢

【Author】 YANG Bao-hua, WANG Li, CHEN Yong-gan (Pharmacy College, Henan University, Kaifeng 475001, China)

【机构】 河南大学药学院河南大学药学院 河南开封475001河南开封475001河南开封475001

【摘要】 采用高分子材料制成硝苯地平缓释片 ,测定其释放度 ,以灰色数学模型进行分析 .结果表明 ,用灰色数学模型对药物释放过程进行拟合 ,拟合精度高 ,结果可靠 .灰色数学模型可用于描述其释药行为 .

【Abstract】 The Nifedipine sustained—release tablets were produced form macromolecule material, its release were determined. Grey Model analyzed for the relase. The research results showed that the gray GM(1,1) model draw up for drug release had a high accuracy and results was trustiness. The paper showed that the Grey GM(1,1) model could be used to precisely predict sustained—release dug release process.

  • 【文献出处】 数学的实践与认识 ,Mathematics In Practice and Theory , 编辑部邮箱 ,2003年11期
  • 【分类号】R91
  • 【被引频次】2
  • 【下载频次】131
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