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天然红心鸭蛋中的类胡萝卜素及对S180肿瘤抑制作用的初步研究

Fringe Study on Carotenoids Extraction of Natural Red Yolkand its Inhibition on S180 Tumour

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【作者】 刘良忠张民王海滨石嘉怿张声华

【Author】 LIU Liang-Zhong,ZHANG Min,WANG Hai-bin,SHI Jia-yi,ZHANG Sheng-hua(College of Food Science and Technology, Huazhong Agricultural University, Wuhan 430070, China)

【机构】 华中农业大学食品科技学院华中农业大学食品科技学院 武汉430070武汉430070武汉430070

【摘要】 本文对天然红心鸭蛋中的类胡萝卜素做了初步分析,同时探讨了红心鸭蛋中的类胡萝卜素对S180肿瘤的作用。初步结果表明,天然红心鸭蛋中的类胡萝卜素包含有虾青素及其它一些种类的类胡萝卜素。天然红心鸭蛋中的类胡萝卜素对肝匀浆MDA的产生有显著的抑制作用, 对昆明小白鼠S180肿瘤具有显著的抑制作用,且具有明显的量效关系。低、中、高剂量组的类胡萝卜素对肿瘤的抑制率分别为23.2%、35.7%和42.9%,对肿瘤小鼠的内脏指数有显著改善作用,并可显著地降低肿瘤小鼠血清MDA含量。

【Abstract】 The paper first analyzed the carotenoids in the red yolks of duck, and probed into the inhibition of the carotenoidson S180 tumour. Several carotenoids, for example, astaxanthin, etc, were found in the red yolk. The carotenoids had a marked inhibitionon MDA and on the proliferation of S180 tumour, and showed a relationship between dosage and effect. The inhibition rates of low,middle and high dosage groups were 23.2%, 35.7% and 42.9% respectively. The carotenoias had a remarkable improving effect onthe internal organs index of tumour carried rats. The serum MDA content of tumour carried rats was markedly depressed.

【基金】 国家博士点基金项目(20020504008)
  • 【文献出处】 食品科学 ,Food Science , 编辑部邮箱 ,2003年11期
  • 【分类号】R73-36
  • 【被引频次】29
  • 【下载频次】189
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