【摘要】 [目的]观察安胎清肝方药治疗妊娠期慢性乙型病毒性肝炎的疗效。[方法]选择安胎药菟丝子、黄芪、黄芩等和清肝药叶下珠、蒲公英等组成安胎清肝方治疗妊娠期慢性乙型病毒性肝炎50例,观察治疗后妊娠情况、肝功能、乙肝病毒标志物和肝纤维化指标的变化。[结果]经治疗后无1例出现流产,谷丙转氨酶、血清胆红素、血清透明质酸等均明显降低,与治疗前比较,差异均有显著性(P<0.01);HBeAg和HBV—DNA的阴转率分别达到30％和32.5％。[结论]安胎清肝法对妊娠期慢性乙型病毒性肝炎有较好的保胎、护肝作用。更多还原

【Abstract】 [ Objective] To observe the therapeutic effect of fetus - soothing and liver - clearing therapy for pregnancy associated with chronic hepatitis B. [Methods] Fifty cases of pregnancy associated with chronic hepatitis B were treated with fetus - soothing and liver - clearing Decoction, which is mainly composed of Semen Cuscutae, Radix Astragali, Radix Scutellariae, Herba Phyllanthus and Herba Taraxaci. After treatment, general state of gravida, indexes of hepatic function, hepatitis B virus (HBV) marker and hepatic fibrosis were detected. [Results] No miscarriage was found in the cases. Serum levels of glutamic - pyruvic transaminase, bilirubin and hyaluronic acid ( HA) were decreased obviously , the difference being significant as compared with those before treatment ( P < 0.01). Ratios of HBeAg becoming negative and HBV- DNA becoming negative were 30.0% and 32.5% . [Conclusion] Fetus - soothing and liver -clearing therapy exerts a good effect in preventing miscarriage and protecting liver for pregnancy associated with chronic hepatitis B.更多还原