【摘要】 目的　对医用诊断X射线工作者染色体畸变断裂点的分布进行分析。方法　采用G显带方法分析外周血淋巴细胞染色体断裂点。结果　 3 7名X射线工作者G显带中期分裂细胞 3 5 45个 ,共有断裂点 146个 ,统计学处理观察值和预期值有显著性差异 ( χ2 =42 82 ,df =2 3 ,P<0 0 1)。 10名对照人员G显带中期分裂细胞 90 8个 ,共有断裂点 17个 ,统计学处理观察值和预期值差异无显著性 (P >0 0 5 )。结论　医用诊断X射线工作者染色体畸变断裂点呈非随机分布 ,其中第 7和 14号染色体断裂点数目的观察值比预期值高 (P <0 0 5 )。更多还原

【Abstract】 Objective To analyze the distribution of the chromosome aberration breakpoints from medical diagnostic X-ray workers.Methods The breakpoints of lymphocyte chromosomes are analyzed using G-banding. Results There are 146 breakpoints among 3 545 metaphase in 37 cases of X-ray workers.There are statistically significant differences between observed values and expected values(χ 2=42.82,df=23,P<0.01).There are 17 breakpoints among 908 metaphase in 10 controls.There are not statistically significant differences between observed values and expected values (P>0.05).Conclusion The chromosome aberration breakpoints of medical diagnostic X-ray workers are non-random.The observed values of breakpoint numbers are higher than those of the expected values in 7 and 14 chromosomes (P<0.05)更多还原