【摘要】 目的 :总结在不同时机应用纳络酮治疗新生儿窒息后脑损伤的临床治疗效果及护理经验。方法 :随机将新生儿窒息 6 1例分为 3组 ,A组 19例 ,生后即脐静脉注射纳络酮 ,并与静脉注射相结合 ,B组 2 2例 ,进入新生儿病房后静脉注射纳络酮 ,C组 2 0例 ,不用纳络酮 ,常规治疗。结果 :A组临床症状消失时间明显短于B、C两组 (P <0 0 5 )。前囟B超检查及血CPK -BB检查结果差异均有显著性 (P <0 0 5 ,P <0 0 1)。结论 :早期连续使用纳络酮治疗新生儿窒息后脑损伤可迅速缓解临床症状 ,这对临床抢救新生儿窒息后脑损伤具有重要意义更多还原

【Abstract】 Objective:To summarize the curative effect of naloxone in different time in treatment of neonatal brain damage after asphyxia.Method:61 newborns were divided into three groups randomly. Group A included 19 cases who received naloxone treatment by intraumbilical vein injection after birth and intravenous injection.Group B included 22 cases who received naloxone treatment just by intravenous injection.Group C included 20 infants who received routine therapy.Result:There was significant difference in symptoms disappear time between group A and group B or C(P<0.05).There was significant difference in anterior fontanel ultrasonic examination and the serum enzyme cpk-bb LEVELS(P<0.05,P<0.01).Conclusion:Naloxone treatment after birth could alleviate clinical symptoms.It may play an important role in treatment of neonatal brain damage after asphyxia.更多还原