【摘要】 目的　 通过对新生儿高胆红素血症患儿进行脑干听觉诱发电位 (BAEP)检测 ,评估高胆红素血症在未发生核黄疸时对脑损害及听力的影响。 方法 　对新生儿高胆红素血症患儿入院后进行脑干听觉诱发电位的测定。 结果 　 49例高胆红素血症患儿中异常BAEP发生率为 3 7%( 18/ 49例 ) ,表现为各波潜伏期 (PL)及波间潜伏期 (IPL)的延长和听阈值的增高 ,听阈值随胆红素浓度的增高而增高 ,经治疗后黄疸消退 ,脑干听觉诱发电位大部分恢复正常。 结论 　高胆红素血症对新生儿可造成听力损害 ,BAEP是检测高胆红素血症患儿听力筛查的重要手段之一更多还原

【Abstract】 Objective To evaluate the damage of hyperbilirubinemia to brain and hearing by brainstem audio electric potential (BAEP) screening in neonates with hyperbilirubinemia but without kernicterus.Methods Forty nine infants admitted with hyperbilirubinemia were screened by BAEP.Results Among them,the incidence of abnormal BAEP with characteristic prolonged latent period of different wave,interval wave and higher threshold of auditory sensation was 37%.The threshold of auditory sensation actually positively correlated with the blood bilirubin level.In Most infants,blood bilirubin level and threshold of auditory sensation turned to normal soon after treatment.Conclusion Hyperbilirubinemia may cause hearing damage in neonates and BAEP is one of effective audiometric devices.更多还原