【摘要】 目的:探讨血清C反应蛋白(CRP)在动脉粥样硬化性血栓性脑梗死(ATCI)发病中的变化及意义。方法:采用免疫浊度法测定62例ATCI患者发病后72小时内及第6～8天,第15天血清CRP浓度,并检测48例对照者的血清CRP浓度。结果:ATCI组患者3个时期血清CRP浓度(mg/L)分别为(11.32±3.16,18.71±5.14,13.61±4.81),均较健康对照(3.75±1.46mg/L)明显增高(P<0.01),中度及重度ATCI患者血清CRP浓度增高明显,且第6～8天的水平最高。结论:血清CRP浓度增高可能在ATCI的发病中具有一定的作用,并与病情程度正相关。更多还原

【Abstract】 Objective: To investigate the changes and clinical implication of serum C-reactive protein(CRP) concentration in the patients with atherothrombotic cerebral infarction(ATCI). Methods: The concentration of serum CRP in 62 patients with ATCI and 48 healthy controls was measured by immune turbidity method. Results: As compared with the controls(3. 75 ± 1. 46mg/L), the concentration of serum CRP (mg/L) were increased in three periods in the ATCI group (11. 32 ± 3. 16, 18. 71±5. 14, 13. 61 ± 4. 81)(P<0. 01), showing a higher serum in medium and in severe patients. Conclusion: highe serum CRP concentration may play a role in the development of ATCI, serum CRP concentration is positive correlation with severity extent of ATCI.更多还原