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银屑病患者血清抗EB病毒抗体的检测

Detection of antibodies against Epstein-Barr virus in sera from patients with psoriasis

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【作者】 段西凌邱练芬胡开华林新瑜薛竟王尚兰吴良章

【Author】 DUAN Xi-ling,QIU Lian-fen,HU Kai-hua,LIN Xin-yu,XUE Jing,WANG Shang-lan,WU Liang-zhang(Department of Dermatology,People’s Hospital of Sichuan Province,Chengdu610072,China)

【机构】 四川省人民医院皮肤科四川省人民医院检验科四川省人民医院皮肤科 四川成都610072四川成都610072四川成都610072

【摘要】 目的:探讨EB病毒感染与银屑病的关系。方法:采用酶免疫法检测53例银屑病患者血清EB病毒抗壳抗原/IgG、IgM抗体,抗早期抗原-D/IgG抗体,抗核心抗原-1/IgG抗体。结果:银屑病患者血清抗EB病毒早期抗原-D/IgG抗体阳性率明显高于正常对照组(P<0.001)。结论:银屑病患者体内EB病毒可能处于激活状态。

【Abstract】 Objective:Study on the relationships between the infection of Epstein-Barr virus(EBV)and psoriasis.Meth-ods:Using the assays of enzyme-immunoassay,the sera were examined in53patients with psoriasis and53normal subjects to detect the antibod ies(IgG,IgM/VCA,IgG/EA-D and IgG/EBNA-1)to EBV.Results:The rate of positive reactions to IgG/EA-D was significantly higher in the patients with psoriasis than that in controls(P<0.001).Conclusion:These re sults suggest that EB virus might be activated in the patients with psoriasis.

  • 【文献出处】 临床皮肤科杂志 ,Journal of Clinical Dermatology , 编辑部邮箱 ,2003年01期
  • 【分类号】R758.63
  • 【被引频次】42
  • 【下载频次】137
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