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哈伯因治疗慢性精神分裂症认知障碍疗效观察

The clinical efficacy of hyperzine on cognitive function of chronic schizophrenics

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【作者】 郑华胜林朱新周春闽颜世英任敏高秉珠

【Author】 Zheng Huasheng, Lin Zhuxin, Zhou Chunmin ,et al. Fuzhou Neuropsychiatric Hospital, Fujian 350008

【机构】 福州神经精神病防治院福州神经精神病防治院 350008350008

【摘要】 目的:观察哈伯因治疗慢性精神分裂症患者智能障碍的临床疗效。 方法:以哈伯因治疗33例与全龟胶囊治疗29例,两组病例于治疗前后均测定胆碱酯酶(ChE)与乙酰胆碱(Ach)浓度。 结果:哈伯因组用药前后Ach浓度有显著差异,与全龟组比较亦有明显差异。患者智力明显提高。 结论:哈伯因治疗慢性精神分裂症患者能提高Ach浓度,对改善认知功能有效。

【Abstract】 Objective: To observe the clinical efficacy of hyperzine on cognitive function of chronic schizophrenics. Method: 33 schizophrenic patients were treated with hyperzine and 29 patients treated with quan gui jiaonang. Clinical effcacy, blood condition of ChE and Ach, cognitive function of these patients were observed. Results : Ach level in hyperzine group was significantly increased after the treatment and was markedly higher than that in quan gui group. Conclusion: Cognitive function of chronic schizophrenics can be significantly improved and Ach level can be increased when treated with hyperzine.

【关键词】 精神分裂症认知功能哈伯因
【Key words】 SchizophreniaCognitive functionHyperzine
【基金】 福州市科学技术委员会资助项目(200350102000641)
  • 【文献出处】 临床精神医学杂志 ,Journal of Clinical Psychological Medicine , 编辑部邮箱 ,2003年01期
  • 【分类号】R749.3
  • 【被引频次】12
  • 【下载频次】59
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