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类肝素寡糖/多糖衍生物抗凝血材料的研究进展
Advances in the Study on Heparin-like Oligosaccharides and Polysaccharide Derivatives-based Anticoagulatory Materials
【摘要】 综述了近年来有关类肝素寡糖以及壳聚糖、透明质酸、软骨素等硫酸 /磺酸化衍生物抗凝血性的研究进展 ;介绍了一些来源于植物的木聚糖、直链淀粉、纤维素、凝胶多糖硫酸化衍生物用于抗凝血的研究 ,以及它们的结构对抗凝血性能的影响
【Abstract】 The latest progress in anticoagulation of heparin-like oligosaccharides and of chitosan-,hyaluronic acid- and chondroitin-sulfated/sulfonated polysaccharide derivatives is reviewed. Research reports on the anticoagulatory applications of sulfated species of plants-extracted polysaccharides such as xylan,cellulose,amylase and curdlan,are mentioned. The influence of their structural features on the anticoagulation is also presented.
【关键词】 多糖;
寡糖;
抗凝血性;
硫酸/磺酸化;
【Key words】 polysaccharide; oligosaccharide; anticoagulation; sulfated/sulfonated;
【Key words】 polysaccharide; oligosaccharide; anticoagulation; sulfated/sulfonated;
【基金】 天津市自然科学基金资助项目 ( 0 2 36 0 4 411)
- 【文献出处】 化工进展 ,Chemical Industry and Engineering Progress , 编辑部邮箱 ,2003年07期
- 【分类号】TQ464
- 【被引频次】14
- 【下载频次】524