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增生性疤痕组织与正常上皮组织FTIR光谱研究

FTIR Study on the Hypertrophicscar and Normal Skin Tissues

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【作者】 东野广智孟庆勇张培华汤少明周群孙素琴胡鑫尧

【Author】 DONYE Guang-zhi, MENG Qing-yong, ZHANG Pei-hua, TANG Shao-ming, ZHOU Qun, SUN Su-qin and HU Xin-rao1. Anlysis Center, Guangdong Medical College, Zhanjiang 524023, China2. Department of Plastic Surgery , Affiliated Hospital of Guangdong Medical College , Zhanjiang 524001, China3. Department of Chemistry, Tsinghua University. , Beijing 100084, China

【机构】 广东医学院分析中心广东医学院附属医院整形外科清华大学化学系清华大学化学系 广东 湛江 524023广东 湛江 524023广东 湛江 524001北京 100084北京 100084

【摘要】 通过对40例疤痕组织和正常皮肤组织的ETIR光谱比较分析发现,由于个体差异,其光谱均可分为三种不同类型。此外,疤痕组织中的胶原、蛋白质、核酸和脂类等生物大分子的吸收峰强度均在不同程度上高于正常皮肤组织,但两者的A1083/A1548并无明显差异。提示疤痕组织中的细胞仍属正常生长,治疗中不应损伤。

【Abstract】 40 cases of hypertrophicscar (HS) tissues and corresponding normal skin tissues were studied by FTIR technique, and the results snowed that all of the HS and normal tissues can be classified into three kinds. Furthermore, the absorption bands of biomacro-molecule in collagen, protein, nucleic acid and lipid of hypertrophicscar are stronger than those of normal tissues. But there is no significant difference in A1083/A1548 between HS and normal tissues. It is suggested that the cells of HS could still be normally growing and should not be scathed in the treatment process.

【关键词】 增生性疤痕傅里叶变换红外光谱法
【Key words】 Hypertrophic scarFTIR
  • 【文献出处】 光谱学与光谱分析 ,Spectroscopy and Spectral Analysis , 编辑部邮箱 ,2003年02期
  • 【分类号】O657.33
  • 【被引频次】5
  • 【下载频次】111
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