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男性不育者精子顶体酶活性影响因素分析

Analysis of Influence Factors of Human Sperm Acrosin Activity

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【作者】 刘睿智沙艳伟许宗革董乃屹辛暨丽李哲王忠山

【Author】 LIU Rui zhi 1, SHA Yan wei 1, XU Zong ge 1, DONG Nai yi 2, XIN Ji li 1, LI Zhe 1,WANG Zhong shan 1 (1. Dept.of Cell Biology, School of Basic Medical Sciences, Jilin University, Changchun 130021, China;2. Jilin Family Planning Research Institute) [

【机构】 吉林大学基础医学院细胞生物学教研室吉林省计划生育研究所吉林大学基础医学院细胞生物学教研室 吉林长春130021吉林长春130021吉林长春130021

【摘要】 目的 :分析某些因素对男性不育者精子顶体酶活性的影响。方法 :分光光度比色法检测3767例男性不育者精子顶体酶活性。结果 :精液液化时间延长组、p H值降低组、白细胞数 >5个 /HP组的精子顶体酶活性均显著低于其相应对照组 ( P<0 .0 0 1 ,P<0 .0 0 1 ,P<0 .0 5 )。顶体酶活性与支原体感染和精浆 As Ab无关 ( P>0 .0 5 ,P>0 .0 5 )。结论 :精液液化时间、p H值和白细胞数影响顶体酶活性 ,精液支原体感染和精浆 As Ab对顶体酶活性无影响

【Abstract】 Objective:In order to study the influence factor of the sperm acrosin activity. Methods:The sperm acrosin activities in 3 767 male infertiles were determined and the influence factors were analyzed. Results:There was a significant difference in normal semen liquefied duration, pH and white blood cells (WBC) under microscope ( P <0.001, P <0.001, P <0.05). The comparison between U.urealyticum negative group and U.urealyticum positive group showed that the acrosin activity was not significant difference ( P >0.05). The comparison between AsAb positive group and AsAb negative group showed the acrosin activity was not significant difference ( P >0.05).Conclusion:Semen liquefied duration, pH and WBC could affect acrosin activity. U.urealyticum infection in semen and AsAb in seminal plasma could not affect acrosin activity. [

【基金】 吉林省计划委员会资助课题 (1999)
  • 【文献出处】 吉林大学学报(医学版) ,Journal of Jilin University of (Medicine Edition) , 编辑部邮箱 ,2003年05期
  • 【分类号】R698.2
  • 【被引频次】15
  • 【下载频次】238
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