【摘要】 目的　调查异体手指复合组织与自体第二足趾同时移植再造拇、手指的临床效果。　方法　以自体甲皮瓣包绕冷冻异体手指复合组织并连第二足趾游离移植为多指缺失者 2 4例 (2 5手 )再造出拇、手指 5 0指。采用信访填表、拍片、门诊复查 15例 (16手 )进行疗效分析。平均随访时间 4年。　结果　再造手指的触、痛及温度觉恢复 ,对掌功能优良 ,供足能胜任步行 ,但 4例植皮区易磨损 ,3例(4足 )趾外翻 ,2例前足底产生胼胝。冷冻或冻干的异体手指移植后无排斥反应 ,供、受体骨与肌腱连接愈合。　结论　异体手指复合组织与自体第二足趾联合移植可减少足趾数丧失 ,多造手指 ,保持供足步行功能。移植物经过冷冻或冻干处理后 ,抗原性很弱 ,无须应用抗排斥反应药物。更多还原

【Abstract】 Objective To investigate the clinical result of reconstructed thumbs and fingers using frozen allogeneic composite tissues of fingers and autogenous toe Methods Fifty thumbs and fingers were reconstructed in 24 patients (25 hands) by allogeneic composite tissues of finger wrappoed by free neurovascular big toe nail skin flap and combined transplantation with autogenous second toe 15 patients were followed up for 4 years in average with examination in the ambulant clinic, communication and X ray photography to evaluate the clinical effect Results Recovered sensory function of the reconstructed fingers as well as good opposition function were seen There were Charcot’s like arthrosis of allogeneic MP and arthroclisisof IP in 2 cases The postoperative gait of the doner’s feet was normal The site of grafted skin on big toe was rubbed easily in 4 cases and the valgus hallexo of the doner’s foot were seen in 3 cases, the plantaris callus in 2 cases Postoperative immunological rejection didn’t elicit The junction between implanted allo phalangen tendon and autophalanges tendon were reliably healed Conclusions This operation gives reconstructed more fingers without sacrificing more toes for patients The walking function of donor foot is good The antigenicity of allogeneic grafts could be abated after preservation under 30℃ or frozen dried更多还原