【摘要】 目的　探讨不同数量的高分子材料丝对许旺细胞活性的影响。　方法　以粘附有许旺细胞的不同数量的高分子材料细丝加入聚乳酸管中 ,在体外用免疫组化染色和细胞端粒酶活性测定等观察许旺细胞活力情况。　结果　在直径为 1 8mm、厚度为 0 3mm的聚乳酸管中放入 480根直径约10 μm的高分子材料细丝时许旺细胞活力比放入 2 40根、960根和不放丝组好。　 结论　在直径为 1 8mm厚度为 0 3mm的PLA管中加入粘附有许旺细胞的高分子材料细丝构建人工神经时以加入 480根丝为最好更多还原

【Abstract】 Objective To investigate the bioactivity of Schwann cells which adhered with different number of vicryl filaments Methods To put variant number of vicryl filaments (diameter 10 μm) which was adhered with Schwann cells into a PLA conduit, and to compare the bioactivity of Schwann cells Results Schwann cells had the best bioactivity when put 480 vicryl filaments into the PLA conduit which with internal diameter of 1 8 mm and wall thickness of 0 3 mm Conclusions One could have the bioactive Schwann cells when put 480 vicryl filaments into that PLA conduit更多还原