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半夏泻心汤不同配伍情况下部分化学成分变化
The Changes of Some Chemical components in Banxiaxiexintang Decoction of Different Combinations
【摘要】 目的 :测定半夏泻心汤不同配伍情况下小檗碱、巴马丁及甘草酸的含量。方法 :复方按药物性味分组 ,高效液相色谱法测定。结果和结论 :不同组合中小檗碱、巴马丁及甘草酸的煎出量不同 ,为研究中医组方理论的化学基础做了初步探索和资料积累
【Abstract】 Objective:The contents of bererine, palmatine and glycyrrhizin acid in Banxiaxiexintang decoction of different combinations were determined by PR HPLC.Method:A Shim pack CLC ODS column was used with a mobile phase of CH 3CN H 2O (31∶69;0.005 moL·L -1 pentanesulfonic acid sodium salt, H 3PO 4: pH 3.0) for bererine andpalmatine, which were detected at the wavelength of 275 nm. A YWG C 18 column was used with a mobile phase of CH 3OH H 2O HAc(62∶37∶1) for glycyrrhizin acid which was detected at the wavelength of 260 nm.Result:each herbs’ combination influences the contents of the 3 components.Conclusion:The experiment is an attempt to study the comical foundation of traditional Chinese prescription.
【Key words】 Banxiaxiexintang Decoction; bererine; palmatine; glycyrrhizin acid; HPLC;
- 【文献出处】 中国中药杂志 ,China Journal of Chinese Materia Medica , 编辑部邮箱 ,2002年05期
- 【分类号】R289.5
- 【被引频次】17
- 【下载频次】434