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血清一氧化氮一氧化氮合成酶与宫缩乏力性产后出血关系的研究
Study of the relationship between serum nitric oxide,nitric oxide synthase and postpartum haemorrage caused by uterine atony.
【摘要】 目的 探讨血清NO及NOS与产后出血的关系及意义。方法 对无妊娠合并症及胎盘因素的 6 1例妊娠足月未临产 ,因臀位、胎儿偏大、骨盆等因素而行剖宫产的孕妇 ,进行术前及术后半小时血清NO及NOS含量的测定 ,并测量产后 2小时内出血量。结果 产后出血组术前及术后NO、NOS含量较非产后出血组明显增高 ,差异极显著 (P <0 0 0 1 )。且术前、术后血清NO及NOS含量与产后出血量呈正相关 ,差异极显著 (P均 <0 0 1 )。结论 测定血清NO及NOS含量 ,可预测产后出血的发生 ,从而正确选择剖宫产时机
【Abstract】 Objective to investigate the relationship and significance between the serum level of nitric oxide(NO),serum nitric oxide synthase(NOS)and the level of postpartum haemorrage(PPH).Methods The serum level of NO and activety of NOS were measured in 61 cases.Before and after 30 minutes of cesarean section on the patients who had a cesarean section for reasons of breech presentation,fetal macrosomia and pelvic factors,et al,but without any pregnant complications and placental factors,the serum NO and NOS levels were measured,and the level of PPH was measured within 2h after opeation.Results The serum level of NO and activity of NOS were significantly higher in PPH group than those of non PPH group(P<0\^001).There was positive correlation between the serum level of NO,NOS before and after operation and the level of PPH(P<0\^01 respectively).Conclusion Measuring the level of serum NO,NOS might forecast PPH,thereby select the proper opportunity of cesarean section.
【Key words】 Postpartum haemorrage\ NO\ NOS\ Cesarean section;
- 【文献出处】 中国实用妇科与产科杂志 ,Chinese Journal of Practical Gynecology and Obstetrics , 编辑部邮箱 ,2002年06期
- 【分类号】R714.4
- 【被引频次】11
- 【下载频次】69