【摘要】 目的 :探讨 40岁以上妇女的妊娠及其对分娩的影响。方法 :回顾性分析 1 989年 1 1月至 2 0 0 0年 1 0月分娩的40岁以上的孕妇 92例 (观察组 )及同期妊娠的 2 0～ 2 9岁孕妇 1 94例 (对照组 )。结果 :观察组不孕史、习惯性流产及子宫肌瘤发生率 (分别为 31 .5 %、9.8%、5 .4% )显著高于对照组 (P <0 .0 0 1或P <0 .0 5) ;其妊娠高血压综合征、前置胎盘、早产发生率 (分别为 2 0 .7%、5 .4%、9.8% )显著高于对照组 (P <0 .0 1或P <0 .0 5) ;观察组剖宫产率 (82 .6 % )较对照组 (57.7% )明显增高 (P <0 .0 1 ) ;观察组巨大儿发生率 (9.8% )显著高于对照组 (3.6 % ) (P <0 .0 5)。两组新生儿出生体重、新生儿窒息、新生儿畸形、围产儿死亡率差异无显著性 (P >0 .0 5)。结论 :尽管 40岁以上的高龄孕妇的妊娠合并症、并发症以及剖宫产率明显增加 ,但总的围产儿结局不受母亲年龄的影响。更多还原

【Abstract】 Objectives:To examine pregnancy outcomes among women above 40 years and older.Methods: A retrospective cohort study,including 92 pregnant women aged 40 or older and 194 controls at age 20～29 years,was conducted.Results: The rates of pregnancy with infertility,habitual abortion,myoma of uterus,pregnancy induced hypertension syndrome,placenta previa and premature delivery were significantly higher in the older group the control group( P <0.001 or P <0.01 or P <0.05).The cesarean delivery rate for the older gravidas was significantly higher than that of the younger controls( P <0.01).The rate of fetal macrosomia in the study group was significantly higher than the control group( P <0.05),whereas the rates of neonatal a sphyxia,deformity,death and mean birth weight were no difference between the two groups( P >0.05)Conclusions: Although maternal morbidity was increased in the older gravidas,the overall neonatal outcome did not appear to be affected.更多还原