【摘要】 目的 :比较曲马多、吗啡、芬太尼术后病人自控硬膜外镇痛 (PCEA)的临床效应。方法 :90例 (ASAⅠ -Ⅱ )手术病人随机分成三组 ,T组 (n =30 )镇痛药液为 0 .6 %曲马多 +0 .0 1%氟哌啶 +0 .15 %布比卡因 ;M组 (n =30 ) 0 .0 0 5 %吗啡 +0 .0 1%氟哌啶 +0 .15 %布比卡因 ;F组 (n =30 )0 .0 0 0 4 %芬太尼 +0 .0 1%氟哌啶 +0 .15 %布比卡因。采用佛山舒贝康 (自控型 )泵 ,选择负荷剂量+持续剂量 +PCA给药模式 ,其剂量分别为 5ml- 2ml/h - 0 .5ml。结果 :①镇痛效应 :VAS评分M组 <T组 <F组 (P <0 .0 1) ;②并发症恶心、呕吐发生率M组 >T组 >F组 (16 .6 %～ 3.3% ) ;嗜睡和瘙痒 :M组 >T组 >F组。结论 :术后行PCEA时 ,三种药物镇痛效应均较满意 ,以吗啡组为优 ,但副作用明显高于曲马多组和芬太尼组。更多还原

【Abstract】 Objective:To compare the clinical of postoperative patient comtrolled epidural analgesia(PCEA)with tramedol or morphine or fentanyl Method:The 90 cases of surgical patients were randomly divided into three groups of 30 each.Group M:0.005% morphine+0.01% droperidol+0.15% bupivacaine.Group F.0.0004% Tentanyl+0.01% droperidol+0.15% bupivacaine.With SuBeiKang PCA Pump in the loading continuous PCA model,the doses were 5ml 2ml/h-0.5ml respectively.Result:(1)In these three groups,Visual analog scall scores was M<T<F group( P <0.01)(2)The incidence of nousea and vomitting:M>T>F group;(16.6%～3.3%)the incidence of somnolence and pruritus:M>T>F group.Conclusion:During post operative PCEA,the analgesia effects of group T,M and F were satisfactory and morphine group is better than T?F.But the aversive side effects such as nousea and vomitting are more than T.F group.更多还原