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Askin瘤4例临床病理分析
Askin tumor:Clinicopathological analysis of 4 cases
【摘要】 目的 :探讨Askin瘤的临床病理特点。方法 :回顾性分析 4例Askin瘤的临床病理资料 ,并作网状纤维与免疫组化染色。结果 :4例Askin瘤为 6~ 2 0岁 ,均发生于胸壁并侵犯肋骨。由少量纤维间质将小圆形瘤细胞分隔成巢状或小叶状。网状纤维染色肿瘤细胞间网状纤维少。免疫组化染色Vim、NSE、S 10 0蛋白阳性数分别为 3/ 4、4/ 4、3/ 4,LCA、CK均为阴性。 2年生存数仅 1例。结论 :Askin瘤是一种特征性的高度恶性肿瘤
【Abstract】 Objective:To investigate the clinicopathological features of Askin tumor.Methods:Four cases of Askin tumor were studied by retrospectively reviewing their clinical data,reticular fiber staining and immunohistochemistry.Results:Four cases of Askin tumor occurred in 6~20 years old growning thoracopulmonary masses and infiltrating the rib.The nest like or lobular structurs composed of small round cells were surrounded by sparse fibrovascular stroma.Among the tumor cells there were no or a few reticular fibers.Immunohistochemical reactivity for vimentin,NSE,and S 100 protein were positive 3/4?4/4 and 3/4,respectively,and those were negative for LCA and CK.Conclusions:Askin tumor is a high malignant neuroendocrine tumor in thoracopulmonary region.
- 【文献出处】 蚌埠医学院学报 ,Journal of Bengbu Medicinae College , 编辑部邮箱 ,2002年01期
- 【分类号】R730.4
- 【被引频次】2
- 【下载频次】26