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氟罗沙星注射液与维生素C配伍的稳定性
The compatible stablity of fleroxacin with vitamin C injection
【摘要】 目的 研究在不同温度 (2 5℃、38℃ )条件下 ,氟罗沙星注射液与维生素C注射液配伍的稳定性。方法 用紫外分光光度法测定供试液中氟罗沙星和维生素C的含量 ,并观察外观、pH值的变化。 结果 配伍液在两种温度下外观、pH值、紫外吸收图谱无显著变化。两药含量呈下降趋势 ,温度越高含量下降越快 ,特别是维生素C在 38℃下 2h含量已降至 95 %。结论 可以配伍使用。
【Abstract】 AMI To study the compatible stability of fleroxacin with vitamin C injection uder two different temperature conditions (25℃,38℃). METHODS Fleroxacin injection and vitamin C injection was determined by ultraviolet spectrophotometry. RESULTS Under two different temperature conditions, none of the admixtures changed in colour pH. Under 38℃, the content of the vitamin C was declined in 2 hours. CONCLUSION Can be used for reference in clinical pracitice.
- 【文献出处】 安徽医药 ,Anhui Medical and Pharmaceutical Journal , 编辑部邮箱 ,2002年01期
- 【分类号】R944
- 【被引频次】1
- 【下载频次】31