【摘要】 目的:探讨补阳还五汤对急性重型颅脑损伤病人的预后影响。方法:51例急性重型颅脑损伤患者,随机分为2组:对照组28例,采用手术+20%甘露醇125 ml+地塞米松5 ml q 8 h,连用3天,后根据病情停用或调整用量,自术后起同用脑活素20 mg或脑组织液20 ml,胞二磷胆碱500 mg.每天1次,10天为一疗程,配以其它支持、营养、抗菌消炎、H₂受体阻滞剂等综合治疗。治疗组23例,在上述治疗基础上,自术后第1天起鼻饲"补阳还五汤",每日2次,连续10天,术后采用彩色血管多普勒（TCD）、脑地形图及颅内压监测仪进行各项指数监测比较。结果:治疗组较对照组各项指数均有好转,伤后1周清醒率提高。结论:对急性重型颅脑损伤病人早期运用"补阳还五汤"是可行的,可以提高病人的1周清醒率,降低应激性溃疡发生率,显著降低颅内压,改善脑组织血液供给,促进脑组织结构和功能的早期恢复。更多还原

【Abstract】 Objective: to evaluate the significante of Buyanghuanwutang for receperation in the prog-nosis of patient with serious craniocerebral injury. Methods: We randomly divided 51 patients into two groups: There were 28 patients of control group and another 23 patients of therapeutic group. Both groups received the following therapeutic regime: (1) Operation, (2) 20% mannital 125 ml and dexamethasone 5 mg iv by drip q 8 h, for 3 days or longer of necessery, (3) cerebral activitin 20 mg or brain tissue 20 ml, CDPC 500 mg iv drip qd for ten days, (4)supportive treatment such as nutrition therapy, antibiotics and H2-Receptor blockers. Beside the above treatment, patients of therapeutic group, received Buyanghuanwutang for Receporation through naso-gaotric tube two times a day for ten days. During the course of treatment, intracranial pressure was monitered, the indexes checked by TCD, and cerebral topography were analysed. Results: The indexes in therapeutic group were better as compared to the control group. The rate of converting consciousness of comatose patients was obviously enhanced. Conclusion: It is rational to use Buyanghuanwutang for receperation in treating serious craniocerebral injury in early stage, it could elevate the rate of converting cousciousness in the first week, reduces the mobidity of stress ulceration. It also reduces the patients ICP, improves the blood supply of brain tissue, accelerates the recovery of cerebral structure and function.更多还原