【摘要】 目的：分析嗜麦芽窄食单胞菌所致呼吸道医院感染的流行、诱因和耐药情况。方法：对我院1999年呼吸道分离出的32株嗜麦芽窄食单胞菌的分布、诱因和抗生素耐药性进行分析。结果：嗜麦芽窄食单胞菌在医院各科分布广泛，肺科分离出18株，占56.3%，其中RICU中分离出6株。药敏显示对泰能耐药，β-内酰胺类和氨基糖甙类耐药率高，对喹诺酮类耐药率稍低。患者均有基础疾病如COPD、癌症等，以及应用广谱抗生素、激素治疗致免疫功能下降，增加了嗜麦芽窄食单胞菌的感染机会。结论：嗜麦芽窄食单胞菌是重要的条件致病菌，对多种抗生素耐药，治疗困难，宜尽早选用合理的抗生素治疗。更多还原

【Abstract】 Objective: To analyse epidemic,predisposing factors and susceptibility to antimicrobial agents of S. maltophilia in nosocomial infection. Methods: S. maltophilia were collected from 32 cases ,the analysis was done the distribution, predisposing factors and drug resistance of S. maltophilia isolated from our hospital in 1999. Results: The distribution results showed that the 32 strains were widely found in many departments of the hospital, 18 strains were detected from department of pulmonary medicine, accounting for 56.3% of the total, 6 strains were detected from the RICU. The susceptible test showed that all isolates were resistant to imipenem,the strains were highly resistant to β-Lactams/ezymase inhibitor and Aminoglycoside; and a lower resistance rate to ciproflxacin.All patients suffered from underlying conditions,antibiotics were used in all patients and stesoids were used in 22 cases. Conclusion: These data indicate that S. maltophilia is an important opportunistic pathogenic bacteria and are multidrug-resistant.更多还原