【摘要】 研究了水牛急性感染肝片吸虫后血细胞免疫反应在抗感染中的作用机制：结果表明．水牛感染后．ＷＢＣ的总体水平在整个感染期高于对照组；ＤＣ中的嗜酸性粒细胞（％）在第 ２周即显著高于对照组直到 １９周．以后下降并接近对照组；嗜中性粒细胞（％）在第５～１６周低于或明显低于对照组．以后两组接近；淋巴细胞（％）在感染后的第２～５周低于或明显低于对照组．以后接近．至第１４周又低于或明显低于对照组直至２１周；单核细胞和嗜碱性粒细胞（％）在整个实验期无显著差异；Ｔ－淋巴细胞（％）从第１周起显著下降，Ｂ－淋巴细胞（％）显著升高．１１周后均与对照组无明显差异；ＲＢＣ－ＣＲ１花环率在２～１６周显著低于对照组．以后逐渐恢复接近对照组，而ＲＢＣ－ＩＣ花环率在２～１８周高于或明显高于对照组。提示水牛在急性感染肝片吸虫后，血细胞的特异性和非特异性免疫反应变化剧烈，共同参与抗肝片吸虫感染机制。更多还原

【Abstract】 Action mechanism of blood cell immune response in water buffaloes against acute infection with F. hepatica was studied. The results showed that after infection of water buffaloes, the total levels of WBC surpassed control group during whole infection; Eosinophiles (%)of DC were high in control group at the 2nd week until 19 weeks, and then dropped and was close to control group; Neutrophiles( %) was low or significantly low in control group within the 5 ?16th weeks; The total levels of lymphocytes (% ) was low in control group during whole infection; T-lymphocytes( %) dropped significantly, but B-lympho-cytes(%) had opposite changes from the first week of infection, with their being close to ones in control group after 11 weeks; REC-CR; and RBC-IC rosette rates dropped and rose during 2 - 16 and 2 - 18 weeks, respectively, and then approached the same between both groups. It was suggested that violent changes of special and non-special immune responses in water buffaloes with acute F. hepatica infection were concerned with the mechanism against infection with F. hepatica together.更多还原