【摘要】 目的 :探讨冷冻治疗肝癌的临床应用技术和效果。方法 :应用 L CS- 2 0 0 0型深度液氮冷冻治疗机 ,对原发性肝癌 6例和继发性肝癌 2例进行了冷冻治疗。结果 :全部患者均手术顺利 ,无手术死亡及严重并发症 ,多数不良反应为疼痛、发热、AL T/AST和胆红素升高。病理显示冷冻区内肝细胞和癌细胞呈凝固性坏死。2例转移性肝癌均于手术后 2年内死亡。 1例巨块型肝癌于手术后 1年死亡。 2例肝癌于手术后 3年死亡。另 3例肝癌现健在 ,已分别存活 3年、3年和 4年。结论 :冷冻治疗肿瘤成功的关键是能否将肿瘤细胞彻底地冷冻致死。冷冻治疗是肝癌治疗的一种手段 ,它有一定的适应证和局限性。如果掌握的好 ,疗效高 ,并发症少更多还原

【Abstract】 Objective:To investigate the technique and its effect of cryosurgery in the treatment of liver cancer.Methods:From 1996 to 1998,8 patients with liver cancer were treated with LCS 2000 cryosurgery machine.Six were with primary liver cell cancer and 2 were with secondary liver cancer.Results:There were no operative mortality and serious complications.The side effects include pain,fever,high ALT/AST and high cholebilirubin.There was coagulation in the normal and liver cancer tissues by post cryosurgery pathological check.Two patients with secondary liver cancer died within 2 years.One patient with gigantic cancer died within one year.Two patients died within 3 years and the other 3 patients are alive for 3,3 and 4 years.Conclusion:The key factor for success in cryosurgery is to freeze the tumor thoroughly.Cryosurgery is a new method to treat liver cancer.There are adaptations and some limits.It should be used choicely.更多还原