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稳恒磁场对小鼠体内细胞诱变作用的研究

Study on Static Magnetic Fields in Inducing Rat’s Cells to Change

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【作者】 吴全义; 端礼荣; 刘方平; 丁翠兰;

【Author】 WU Quan yi 1,DUAN Li rong 2,LIU Fang ping 1,DING Cui lan 1 (1.Department of Physics, the Zhenjiang Medical College; 2.Department of Hygieology,the Zhenjiang Medical College,Jiangsu Zhenjiang 212001,China)

【机构】 镇江医学院物理学教研室; 镇江医学院预防医学教研室; 镇江医学院物理学教研室 江苏镇江212001; 江苏镇江212001; 江苏镇江212001;

【摘要】 目的 :研究稳恒磁场对小鼠骨髓嗜多染红细胞 (PCE)微核率和血象分析的影响。方法 :用磁场强度为 5 2mT的稳恒磁场作用于小鼠 ,每天 2次 ,每次 2h ,10d后检测微核率和血象分析。结果 :表明实验组小鼠微核率较阴性对照组明显增高 (P <0 .0 5 ) ,较阳性对照组仍有显著性差异 (P <0 .0 1) ,而红细胞和白细胞及其分类无明显变化。结论 :提示当小鼠受到稳恒磁场作用时细胞微核率增加 ,可能会起诱变作用

【Abstract】 Objective: In this paper,we studied the effect of the static magnetic fields on the microncleus in PCE of the mouse bone marrow and blood analysis.Methods:52 mT static magnetic fields were used, in a frequency of twice every day for two hour each time.After 10 days the micronuclei rate of mouse bone marrow and blood cell were determined.Results:There were significant differences between experiment group and control group (<0.05),but the change of the number of blood cell was not significant. Conclusion: The experiment demonstrated that static magnetic fields probably induced biological cells to change.

【关键词】 稳恒磁场; 小鼠; 微核试验; 血象分析; 诱变性;
【Key words】 Static; Magnetic field; Microncleus; Blood analysis; Inducing;
  • 【文献出处】 镇江医学院学报 ,Journal of Zhenjiang Medical College , 编辑部邮箱 ,2001年05期
  • 【分类号】R312
  • 【下载频次】38
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