【摘要】 目的　观察丝虫病防治后期残存微丝蚴血症者的传播作用。　方法　 1984～ 1996年 ,在以嗜人按蚊为主要传播媒介的马来丝虫病流行区 ,选定 3个村为观察区 ,终止防治措施进行观察。　结果　人群微丝蚴率≤ 1.0 3%、微丝蚴密度大多≤ 10条 /12 0 μl的裕农和台子村 ,分别在 5年和 10年微丝蚴率和嗜人按蚊感染率均降为 0 ;微丝蚴率 1.36 % ,微丝蚴密度大多≤ 2 0条 /12 0 μl,有极少数较高密度微丝蚴血症者 (>5 0条 /12 0 μl)的石头村 ,于 10年后仍有新检出病例和感染蚊 ,13年后微丝蚴率仍维持在 0 .2 7%。　结论　少数较高密度微丝蚴血症者作为嗜人按蚊感染源作用较强。但随着残存微丝蚴血症者的陆续转阴 ,微丝蚴密度的降低 ,人们防蚊意识增强和社会与自然因素的制约 ,裕农和台子村丝虫病传播已被阻断 ,石头村丝虫病传播正趋于阻断。更多还原

【Abstract】 Objective To observe the transmission role of residual microfilaremia in late stage of malayan filariasis control. Methods In malayan filariasis endemic area with main vector of Anopheles anthropophagus, 3 villages were selected for studying the transmission role of residual microfilaremia after the control measures had been halted from 1984 to 1996. Results In Yunong and Taizi villages with microfilaria (mf) rate ≤1.03% and mf density ≤10/120 μl in most cases, the mf rate and An. anthropophagus infection rate dropped to zero in 5 and 10 years later respectively, while in Shitou village with mf rate 1.36% and mf density ≤20/120 μl in most cases, but few cases with mf density >50/120 μl, newly microfilaremia and infected mosquito could be detected out at the 10th year, and the mf rate still remained to be 0.27% at the 13th year after the control measures being halted. Conclusion The few cases with higher mf density were the chief resources infecting An. anthropophagus, and that along with the negative reversion of the microfilaremia cases, decrease of the mf density, enhence of the health protection of the massess and development of the social-economy, the filariasis transmission would be interrupted in the 3 villages.更多还原