【摘要】 目的22种抗菌消炎中药有效成分对痤疮丙酸杆菌(P.acne,Propionibacteriumacne)的抑制作用。方法进行22种中药有效成分药敏实验。结果丁香酚、桉叶素对P.acne具有高敏作用;黄芩甙、大黄素等10种药物对P.acne具有中敏作用;油镜下观察发现,抑制P.acne后较抑制前细菌数量/单位面积明显减少,大部分细菌溶解死亡,失去正常形态。结论丁香酚、桉叶素和其它中药有效成分对P.acne具有体外抑制作用。更多还原

【Abstract】 Objective To investigate the inhibitory effects of Propionibacterium acnes (P.acnes) by 22 effective components of traditional Chinese medicines. Methods The susceptibility tests of P.acnes to 22 effective components of traditional Chinese medicines were performed. Results P.acnes was highly sensitive to both eugenol and cineole, and moderately sensitive to baicalin, emodin and others. The number of bacteria per oil field decreased obviously under microscopy and bacteriolysis was found after the treatment with those components. Conclusion Eugenol, cineole and other components of traditional Chinese medicines can inhibit P.acnes in vitro.更多还原