【摘要】 目的　进一步提高对肺栓塞的认识及探讨 5 0年来北京协和医院肺栓塞基础病因的变迁。方法　对北京协和医院 195 0～ 2 0 0 0年诊断的 2 39例肺栓塞病例进行回顾性分析。结果　 195 0～1982年和 1983～ 1990年两个时期内 ,北京协和医院每年平均诊断肺栓塞约 3例 ,1991～ 1997年和1998～ 2 0 0 0年两个时期内 ,每年平均诊断肺栓塞病例分别为 8例和 2 0 6例。四个不同时期内肺栓塞主要基础病因 (深静脉血栓形成、心脏病、恶性肿瘤、结缔组织疾病 )在同期肺栓塞病例中的发生率现在已有明显变化。深静脉血栓形成合并肺血栓栓塞症的发病较前有所增加。结论　当前肺栓塞的发病有增加趋势 ,深静脉血栓形成已成为肺栓塞的最主要的基础病因更多还原

【Abstract】 Objective To highlight the understanding of pulmonary embolism(PE), and analyze the trends of underline diseases of PE from Peking Union Medical College(PUMC) Hospital in the last half century. Methods 239 cases of PE were reviewed retrospectively from 1950 to 2000 in PUMC Hospital. Results In the first and second periods (1950～1982, 1983～1990), about 3 cases of PE were diagnosed annually, but in the third (1991～1997) and fourth periods (1998～2000), 8 cases and 20.6 cases of PE were found annually. The incidences of underline diseases of PE, such as deep venous thrombosis (DVT), cardiac disease, malignancy and connective tissue disease varied in different periods. The morbidity of DVT with PE was dramatically enhanced recently. Conclusion There is an increasing trend of incidence of PE in the last half century. DVT events become the most common underline disease or risk factor of PE.更多还原