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贫血患儿红细胞免疫功能观察

THE OBSERVATION OF RED CELL IMMUNE FUNCTION IN CHILDREN WITH ANE-MIA

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【作者】 刘壮李树全苏瑞琼谢湘芝

【Author】 Liu Zhuang, Li Shuquan, Su, Ruiqiong, Xie Xiagzhi Department of Pediatrics, The First Affiliated Hospital of GuangxiMedical University

【机构】 广西医科大学第一附属医院儿科广西医科大学第一附属医院儿科 530021530021530021

【摘要】 为了解贫血患儿的红细胞免疫功能,对 85例贫血患儿(缺铁性贫血 29例、急性白血病 26例、地中海贫血 18例、再生障碍性贫血 12例)进行了红细胞 C3b受体花环率(RBC-C3bRR)和红细胞免疫复合物花环率(RBC-ICR)测定。结果显示所有贫血患儿RBC-C3bRR均显著低于对照组儿童(P<0.01),缺铁性贫血和再生障碍性贫血患儿 RBC-ICR与对照组比较无明显差异(P>0.05),急性白血病患儿 RBC-ICR高于对照组(P<0.05),地中海贫血患儿 RBC-ICR则显著高于对照组(P<0.01)。贫血患儿容易感染可能与红细胞免疫功能低下有关。

【Abstract】 In order to investigate the changes of red cell immune function in children with anemia, we measured the red cell immune function, red cell C3breceptor rosette rates (RBC-C3bRR) and red cell immune complex rosette rates (RBC-ICR). in 85 cases of anemia children who were 29 cases of iron deficiency anemia, 26 cases of acute leukemia, 18 cases of thalassemia and 12 cases of aplastic anemia. The result showed that: (1 )RBC-C3bRR decreased remark- ably in all anemia patients (P<0. 01 ); (2)as for BRC-ICR, they were the same in iron defi- ciency anemia and aplastic anemia (P>0. 05),increased significantly in acute leukemia (P< 0. 05) and increased remarkably in that assemia (P<0. 01 ) compared with control children, respectively.

【关键词】 贫血红细胞免疫
  • 【文献出处】 中国小儿血液 ,China Child Blood , 编辑部邮箱 ,2001年02期
  • 【分类号】R725.5
  • 【被引频次】6
  • 【下载频次】39
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